After Will Graham has an involved dream about killing Dr. Lecter, Jack assembles the team to investigate a killer who seemingly uses trained bears as murder weapons. Later that day, Will also meets Margot Verger, another one of Dr. Lecter's clients. She wants to kill her brother, and Lecter's prescription for her problem is to go through with it. When he sticks his nose into the case, he diagnoses the killer with "species dysphoria." As it turns out, the suspect -- who we'll now call "Man-Bear" -- built power armor based on a long-extinct cave bear. Will Dr. Lecter use him in his battle with Will?
Justin is convinced Erik hates Bryan Fuller, but Erik is not so convinced himself. Both reveal themselves to know entire too much about Thomas Harris' books and the films based upon them. The mumblecore throughout the episode leaves Erik assuming Mason Verger's sister is named Monica. Justin defends the position that Fuller actually finished Hannibal before its cancellation. Erik asserts cats kill to unlock achievements. Justin learns about "waifu." Erik admits he cannot do a Mads Mikkelsen impression, and Jim Pembry's mustache gets a name-check. Also, the appearance of the real Scott Thompson leads to a digression about The Kids In The Hall.